This study examines technological transformation through the relationship between knowledge inputs and innovation, focusing on R&D, digital technologies, and the Learning capacity of the organisation. The aim is to identify Industry 5.0 strategies linked to a human-centric approach, particularly skills matching and job satisfaction. Combining data from ECS 2019 and ESJS 2021, the analysis reveals that digital technologies and the Learning capacity of the organisation drive enterprise innovation. However, digital technologies prove disruptive, leading to skills underutilisation. In contrast, investments in the Learning capacity of the organisation promote organisational innovation and better skills utilisation. Employees in industries with higher investments in the Learning capacity of the organisation report greater satisfaction with their job's match and more adequate use of their skills. This research highlights the crucial importance of the Learning capacity of the organisation in Industry 5.0 strategies, contributing to both innovation and employee empowerment, thus complementing investments in Industry 4.0 technologies.